Resistant dextrin can increase satiety and improve blood sugar levels in healthy adults: RCT

The data published in the European Journal of Nutrition also showed that 14 grams of the resistant dextrose per day resulted in a significant reduction in blood pressure even in people of normal weight after 28 days.

The new study was welcomed by Laetitia Guerin-Deremaux, Head of Nutrition and Health, R&D, Roquette, who told NutraIngredients-USA: “This new clinical demonstration of a long-term effect of nutrios on satiety-related parameters, blood sugar management, and blood pressure can be achieved through the Modulation of the gut microbiota will be explained, which has already been described for nutrient-soluble fiber.

“According to the definition of prebiotics proposed by ISAPP *, we can assume that soluble fiber in nutriose is a prebiotic. Why? We already know that nutriose is a substrate that is selectively utilized by host microorganisms, and with this new study we are further developing our bundle of evidence on the proven health benefits of nutriose. “

Weight management potential

Guerin-Deremaux added that weight control is a top motivator for two out of three consumers who say they changed their diets in the last year, according to Innova Market Insights **.

“Being hungry is the biggest barrier to sticking to healthy eating habits, and it gives manufacturers the opportunity to incorporate and highlight filling ingredients in new products,” she noted. “Among the consumers who are on a diet, the high protein and high fiber types are the most commonly followed types. When it comes to purchasing decisions, little sugar and little fat have the greatest influence. In addition, most consumers say they are actively avoiding or reducing their sugar intake. “

Roquette Nutriose is a range of soluble fiber derived from GMO-free wheat or corn. The new study builds on previous results showing the ingredient’s potential for weight loss in a study of overweight Chinese men (Guérin-Deremaux et al., 2011, Nutrition Research, Vol. 31, pp. 665-672).

Study details

The new study included 20 normal weight and 16 overweight adults who were randomly given either 14 grams of nutriose or placebo (maltodextrin) per day for 28 days. This was followed by 28 days of no intervention (the “washout” phase) before the participants were switched to the other intervention for a further 28 days.

The results showed that, compared to controls, chronic nutriose supplementation was associated with higher saturation values ​​after 14 and 28 days. However, no significant changes were recorded in either group in terms of energy intake and body measurements such as body weight, body fat, waist circumference and hip circumference.

The researchers also note that the resistant dextrin (RD) was linked to a decrease in glycemic response to an intervention drink in the morning.

“Longer-term intervention studies are needed to determine whether the consumption of RD can help regulate body weight and affect metabolic health,” the researchers write.

The researchers also noted improvements in systolic blood pressure after 14 days, but these were limited to those of normal weight and not to the overweight participants.

“From a mechanistic point of view, studies on the different effects of RD on the microbiota of normal and obese individuals could help explain our findings,” they wrote before concluding: “The observed potential antihypertensive properties of RD are of interest but require further investigation . “

Source: European Journal of Nutrition
Published online in advance, doi: 10.1007 / s00394-021-02618-9
“Effects of Resistant Dextrin (NUTRIOSE) Supplementation on Satiety, Glycemia and Related Endpoints in Healthy Adults”
Authors: MR Hobden, et al.

* Gibson et al. 2017, “Expert consensus document: Consensus declaration of the International Scientific Association for Probiotics and Prebiotics (ISAPP) on the definition and scope of prebiotics”, Nature Reviews Gastroenterology & Hepatology, Vol 14, pp. 491–502, doi: 10.1038 / nrgastro 2017.75

** Innova Market Insights 2020 – Nutrition and Weight Loss Trends Worldwide