Subjects ” General neurology
HealthDay News – Recurrent venous thromboembolism rates are higher than expected in subsegmental pulmonary embolism patients who are treated without anticoagulation and do not have proximal deep vein thrombosis, according to a study published online Nov. 23 in the Annals of Internal Medicine.
Grégoire Le Gal, MD, Ph.D., of the Center Hospitalier Régional et Universitaire de Brest in France, and colleagues examined the rate of recurrent venous thromboembolism in patients with subsegmental pulmonary embolism performed without anticoagulation in a prospective cohort study at 18 sites between February 2011 and February 2021. Patients underwent bilateral venous ultrasound of the lower extremities at diagnosis; if the result was negative, it was repeated a week later. Patients without deep vein thrombosis received no anticoagulant therapy.
After the predefined stop rule had been fulfilled in 292 of an estimated 300 patients, the recruitment was terminated prematurely. The researchers found that the primary outcome of recurrent venous thromboembolism occurred in eight of the 266 patients included in the primary analysis during the 90-day follow-up period, for a cumulative incidence of 3.1 percent. In patients with single and multiple isolated subsegmental pulmonary embolism, the incidence of recurrent venous thromboembolism during the 90-day follow-up was 2.1 and 5.7 percent, respectively. None of the patients had a fatal recurrent pulmonary embolism.
Continue reading
“Our study can inform patients and clinicians about the risks of treating an isolated subsegmental pulmonary embolism without anticoagulation,” the authors write.
Summary / full text (subscription or payment may be required)
Subjects:
General neurology thromboembolism
Would you like to read more?
Please log in or register first to view this content.
Login Register
Open minded
Next post in General Neurology
Close
Include more information on the rate of recurrent VTE higher than expected for subsegmental PE
Loading… 
Include more information on the rate of recurring VTE higher than expected for subsegmental PE
Loading…
Include more information on the rate of recurring VTE higher than expected for subsegmental PE
Loading…
Include more information on the rate of recurrent VTE higher than expected for subsegmental PE
Loading…
Would you like to see more content from Neurology Advisor?
Register now for free to access unlimited clinical news with personalized daily tips for you, Full-length features, case studies, conference coverage, and more.
{{login-button}} {{register-button}}
Would you like to read more?
Please log in or register first to view this content.
Login Register
