Infectious Disease
Progress in reducing antibiotic consumption levels despite stewardship push
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Antibiotic use in the United States dropped significantly from 1999 to 2018, although that decline has not occurred over the past decade despite pressure on antimicrobial responsibility, researchers reported in the Open Forum Infectious Diseases.
The United States has not seen a decrease in total antibiotic use in the past 10 years.
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Molly PeterseNo
Aaron AR Tobian
“Antibiotic resistance is a major global public health problem, and in 2014 the US set targets to reduce inappropriate use of antibiotics. Hence, trends in antibiotic use are important to clinicians and public health professionals. ” Molly Petersen, ScM, a data analyst in the Department of Pathology at Johns Hopkins University School of Medicine, and Aaron AR Tobian, MD, PhD, a professor of pathology, medicine, oncology, and epidemiology at the Johns Hopkins University School of Medicine and Bloomberg School of Public Health, said Healio.
Petersen, Tobian, and colleagues conducted a cross-sectional study using data from the National Health and Nutrition Examination Surveys (NHANES) to assess the prevalence of the past 30 days of non-topical ambulatory antibiotic use and the change in prevalence over two periods, from 1999 to 2002 to 2015- 2018 and from 2007-2010 to 2015-2018.
The study showed that the overall prevalence of non-topical outpatient antibiotic use in the last 30 days, adjusted for age, gender, race / ethnicity, poverty status, time of interview and insurance status, increased significantly from 4.9% (95% CI, 3.9 %) changed. and 5%) to 3% (95% CI, 2.6% and 3%) from 1999-2002 to 2015-2018, with the largest decline occurring in children aged 1 year or younger, the researchers reported. However, they did not find any significant change (adjusted prevalence terrace [adjPR] = 1; 95% CI, 0.8, 1 and 2) from 2007-2010 to 2015-2018.
The researchers found that age was significantly related to antibiotic use, noting that children aged 0 to 1 year had significantly higher antibiotic use than all other age categories over 6 years old and that non-Hispanic Black was negative was associated with antibiotic use compared to non-Hispanic White (adjPR = 0.6; 95% CI, 0.4 and 0.8).
“Antibiotic use is higher than recommended for adequate public health. It is important for clinicians to remember their role in reducing antibiotic use, ”said Petersen and Tobian. “We also hope this article will complement the literature for those involved in antibiotic stewardship programs.”
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