Neurological
Obsessive-compulsive disorder associated with increased risk of ischemic stroke
HealthDay News – Adults with obsessive-compulsive disorder (OCD) are at increased risk of ischemic stroke, according to a study published online in Stroke on May 27.
Mu-Hung Chen, MD, Ph.D., of Taipei Veterans General Hospital in Taiwan, and colleagues used data collected from 28,064 adult patients with OCD and 28,064 age, gender, and comorbidity matched controls between 2001 and 2010. Patients were identified who developed ischemic and hemorrhagic stroke by the end of 2011.
The researchers found that patients with obsessive-compulsive disorder, particularly middle-aged and elderly adults, had an increased risk of developing ischemic stroke during follow-up compared to non-OCD controls (hazard ratios 3.02, 2.66, and 3.46). No difference in the cumulative hazard ratio of hemorrhagic stroke was found between the OCD and non-OCD groups. Compared to no use, short- and long-term use of obsessive-compulsive disorder in patients with obsessive-compulsive disorder was not associated with ischemic or hemorrhagic stroke.
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“Our results remind clinicians to closely monitor blood pressure and lipid profiles, which are known to be associated with stroke in patients with obsessive-compulsive disorder,” a co-author said in a statement. “More research is needed to understand how the mental processes associated with obsessive-compulsive disorder can increase the risk of ischemic stroke.”
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Subjects:
General Cardiology Neurobehavioral Disorder Obsessive Compulsive Disorder Stroke Ob