Neurological

Nocturnal excitement in connection with long-term life course, overall mortality

HealthDay News – According to a study published online April 20 in the European Heart Journal, nocturnal arousal stress (AB) is linked to long-term cardiovascular (CV) and all-cause mortality in women and possibly men.

Sobhan Salari Shahrbabaki, Ph.D., of the University of Adelaide, Australia, and colleagues quantified AB in three cohort studies using overnight polysomnograms of 2,782 men in the Osteoporotic Fractures in Men Study (MrOS) sleep study at 424 Women measured in the Osteoporotic Fracture Study (SOF) and 2,221 men and 2,574 women in the Sleep Heart Health Study (SHHS).

The researchers found that 665 men died, including 236 life-course deaths, during 11.2 years of follow-up in MrOS; 105 women died, including 47 life-course deaths, during the 6.4-year follow-up period in SOF; and 987 participants died, including 344 CV deaths, during 10.7 years of follow-up in SHHS. After adjusting for common confounding factors, AB in women with all-cause mortality (SOF: hazard ratio, 1.58; SHHS women: hazard ratio, 1.21) and CV mortality (SOF: hazard ratio, 2.17; SHHS- Women: hazard ratio, associated) associated. 1.60). The association between AB and all-cause mortality and CV mortality was less clear in men.

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“Although there are still many gaps in our knowledge of the relationship between sleep and CVD to be investigated in the coming years, this study provides solid evidence of the importance of sleep quality for better life course health,” write the authors of an accompanying editorial.

Abstract / full text

Editorial

Subjects:

Cardiovascular diseases sleep sleep disorders

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