Neurological

Levodopa for Painless Legs and Moving Toes Syndrome: A Case Study

Subjects ” Movement disorders

In a 60-year-old woman diagnosed with painless legs and moveable toes associated with cerebellar-type multiple system atrophy, treatment with levodopa was associated with complete resolution of involuntary movements, according to a clinical case published in Neurology.

The patient presented with signs and symptoms consistent with multiple system atrophy and a 4 year history of involuntary movements consisting of painless, semi-rhythmic, semi-continuous flexion and extension of the toes.

A comprehensive examination, including nerve conduction studies and magnetic resonance imaging scans of her lumbosacral spine, was unremarkable. Dopamine transporter imaging was completed due to a slight stiffness in her right arm. The results showed reduced uptake bilaterally, which was more pronounced on the left side.

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The patient was diagnosed with painless legs and flexible toes associated with multiple system atrophy, and involuntary movements completely disappeared after levodopa treatment.

reference

Araki T, Mukai T, Araki T. Treatment of painless legs and movable toe syndrome associated with multiple system atrophy with levodopa. Neurology. Published online May 27, 2021. doi: 10.1212 / WNL.0000000000012303

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Movement Disorder Treatments

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