Infectious Disease
Investigation of the yield of H. pylori biopsies after negative tests
November 24, 2021
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LohJ et al. Are H. pylori biopsies warranted in patients with previous negative results? Presented at: ACG Annual Scientific Meeting; 22.-27. October 2021; Las Vegas (hybrid meeting).
Disclosure:
Foster does not report any relevant financial information.
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C. Jonathan D. Foster, DO, FACOI, spoke to Healio about the benefit of repeated Helicobacter pylori biopsies in patients with previously negative tests.
The researchers who presented the study at the ACG’s annual scientific meeting assessed the frequency and yield of repeated endoscopic H. pylori tests in patients who had previously had negative biopsies or previously negative urea breath or stool antigen tests.
The results showed that in patients who previously had a negative biopsy, only a small fraction of subsequent biopsies were positive for H. pylori. Likewise, the percentage of positive biopsies in those with a negative urea breath test or negative stool antigen test was also low.
Foster, medical director of gastroenterology and advanced endoscopy at Jefferson Health New Jersey, noted that this study provides “an interesting insight” into whether clinicians may be performing unnecessary endoscopies and overusing resources.
“Are we giving patients unnecessary anesthesia and taking biopsies that may not be indicated? I think that’s something to look out for in the future, ”said Foster.
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