Infectious Disease

Contact precautions reduce MRSA transmission in VA hospitals by almost 50%

April 11, 2021

1 min read

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Disclosure:
Khader reports that he received grants from the CDC while conducting this study. In the study you will find all relevant financial information from all other authors.

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According to a study published on JAMA Network Open, researchers estimated that contact precautions were linked to a nearly 50% reduction in MRSA transmission rates in adult patients in more than 100 Veterans Affairs hospitals.

“[This] should lead to a reduction in the number of MRSA infections, many of which will occur after patients are hospitalized. “ Karim Khader, PhD, MStat, MRS, Healio said, a research fellow professor of epidemiology in the medical school of the University of Utah. “Contact precautions combined with universal monitoring are an effective measure to reduce the transmission of MRSA.”

Karim Khader Pullquote

Khader and colleagues developed mathematical models to estimate the relationship between contact precautions and MRSA transmission in more than 2 million patients in 108 Veterans Affairs (VA) hospitals. The models “take into account the epidemiology of MRSA transmission to estimate the underlying transmission rate,” they said.

There were more than 5.6 million admissions among the patients in the study – 14.1% of them “believed to have had exposure arrangements with more than 8.4 million MRSA surveillance tests,” the researchers wrote.

According to the study, the reduction in MRSA transmission between 2008 and 2017 was between 43% (95% believable interval) [CrI]38% -48%) to 51% (95% CrI, 46% -55%). Overall, Khader and colleagues estimated that contact precautions reduced MRSA transmission by 47% (95% CrI, 45% -49%).

Larger facilities (RR = 0.84; 95% CI, 0.74-0.96) and facilities with higher compliance with the admissions screen (RR = 0.74; 95% CI, 0.58-0.96) recorded in Related to contact precautions, greater transmission reductions than smaller facilities and facilities with low screening compliance.

Khader said the limitations of the study included the inability to obtain information about compliance with the contact precautions.

“There are other factors that can affect the transmission of MRSA in addition to contact precautions, including antibiotic use, that were not explicitly considered in this study,” said Khader. “This limitation could be addressed in a future analysis by adding additional patient care factors to our underlying model, which may also be associated with changes in the transmission of MRSA.”

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