Neurological
A diet high in omega-3 fatty acids reduces migraines in adults
Subjects ” Migraines and headaches
HealthDay News – Interventions that increase dietary intake of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), with or without a decrease in linoleic acid, alter bioactive mediators involved in migraines and reduce headaches, but they do not improve headaches Quality of life, according to a study published online on June 30th in the BMJ.
Christopher E. Ramsden, MD, of the National Institute on Aging in Baltimore, and colleagues conducted a three-arm study of 182 participants with migraines for five to 20 days per month. Participants were randomly assigned to the H3 diet (increasing EPA + DHA to 1.5 g / day and keeping linoleic acid at about 7 percent of energy; 61 participants), the H3-L6 diet (increasing EPA + DHA on 1.5 g / day and reducing linoleic acid to ≤1.8 percent of energy; 61 participants) or control diet (keep EPA + DHA at <150 mg / day and linoleic acid at about 7 percent of energy; 60 participants).
When compared to the control diet, the researchers observed an increase in the circulating antinociceptive mediator 17-hydroxydocosahexaenoic acid in the H3-L6 and H3 diets. Both the H3-L6 and H3 diets saw improvements in the test to assess the effects of headache on quality of life, but these were not statistically significant. The H3-L6 and H3 diets reduced total headache hours per day, moderate to severe headache hours per day, and headache days per month compared to the control diet. The decrease in headache days per month was greater for the H3-L6 diet than for the H3 diet.
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“This study provides biologically plausible evidence that pain can be treated by targeted dietary changes in humans,” the authors write. “Collective results suggest causal mechanisms linking n-3 and n-6 fatty acids to nociception and open the door to new approaches to treating chronic pain in humans.”
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Subjects:
Diet and Exercise General Pain Migraines Migraines and Headache Pain Management
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