Infectious Disease

Variations in Pediatric Sepsis Outcomes in the US

HealthDay News – For children with severe sepsis, results will vary based on race or ethnicity and insurance status. This is according to a study published online December 14 in The Lancet Child & Adolescent Health.

Hannah K. Mitchell, BMBS, Philadelphia Children’s Hospital, and colleagues conducted a retrospective cohort study using data from the database for inpatient children from the 2016 Health Care Costs and Usage Project. The association between race or ethnicity and insurance status and hospital mortality was studied in 12,297 children with severe sepsis admitted to 1,253 hospitals. The last cohort included 9,816 children.

The researchers found that black children were more likely to die compared to white children (adjusted odds ratio 1.19), reflecting higher death rates among blacks in the southern and western United States (adjusted odds ratio 1.30 and 1, respectively) , 58). There was evidence of prolonged hospital stays in Hispanic and black children (adjusted risk rates 0.94 and 0.88, respectively), particularly in black newborns (adjusted risk rates 0.53). No difference in survival was found for publicly and privately insured children. Increased mortality was observed in connection with the status of “other” insurance (self-payment, no fee and other: adjusted quota ratio, 1.30).

“Future research should look for further differences in sepsis care and outcomes, and examine the mechanisms underlying their existence,” the authors write. “A clearer understanding of the reasons for these differences will allow health systems to develop interventions to address them.”

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Pediatric Sepsis

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