Infectious Disease

The UK doesn’t suggest giving Pfizer vaccine to sufferers with a historical past of allergic reactions

December 09, 2020

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UK health officials have advised against giving Pfizer and BioNTech’s COVID-19 vaccine to anyone with a history of allergic reaction, CNN and other outlets reported.

The guidance is in response to two health care workers who developed symptoms the day after vaccination.

The UK approved the messenger RNA vaccine last week. U.S. regulators are reviewing the vaccine’s dates this week to approve its use in the U.S.

The Medicines and Health Products Regulatory Authority, the UK agency responsible for verifying the safety of medicines, has made the following general recommendations for the use of the vaccine:

  • Medical treatment and supervision are required if an infrequent anaphylactic event occurs during vaccine administration.
  • Vaccine administration should be postponed in patients with acute severe febrile illness.
  • Patients receiving anticoagulant treatment or a bleeding disorder that contraindicates intramuscular injection should only receive the vaccine if the benefits outweigh the risk of vaccination.
  • Patients with weakened immune systems may experience a decreased immune response to the vaccine.
  • The vaccine may not protect all recipients.
  • There are no data on the use of the Pfizer vaccine in people who received another COVID-19 vaccine.

References

Reynolds E et al. CNN. Allergy alert for Pfizer / BioNTech vaccine according to UK health workers with a history of allergy. https://www.cnn.com/2020/12/09/health/covid-vaccine-allergies-health-workers-uk-intl-gbr/index.html. Accessed December 9, 2020.

MHRA. REG 174 Information for UK Health Professionals. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/941452/Information_for_healthcare_professionals.pdf. Accessed December 9, 2020.

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