Infectious Disease

One other examine experiences persistent signs in COVID-19 survivors

February 19, 2021

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Logue does not report any relevant financial information. In the study you will find all relevant financial information from all other authors.

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About 30% of patients with COVID-19 who participated in a study at the University of Washington reported persistent symptoms 3 to 9 months after the onset of the disease. This is evident from the results published in JAMA Network Open.

Other studies have also reported persistent symptoms in COVID-19 survivors, even in young adults. In Wuhan, China, where the pandemic originated, 76% of patients said they still have symptoms 6 months after being infected.

Persistent COVID Symptoms Chart

Source: Logue JK et al. JAMA Netw Open. 2021; doi: 10.1001 / jamanetworkopen.2021.0830.

“Our research shows that the health consequences of COVID-19 extend well beyond the acute infection, even in patients with mild illnesses.” Jennifer K. Logue, BS, A scientist at the University of Washington Lab Medicine and colleagues wrote in the new study. “To fully understand the effects of this evolving viral pathogen, extensive long-term research is required.”

Logue and colleagues enrolled a cohort of 234 adults with COVID-19 and collected symptom data at the time of illness or post-reported symptom data during a 30-day registration visit. A total of 177 participants answered a questionnaire about persistent symptoms 3 to 9 months after the onset of their illness.

Among them, 31% (55 out of 177) reported symptoms 3 to 9 months after the onset of the disease. A total of 32.7% (49 of 150) of outpatients, 31.3% (five of 16) of hospitalized patients, and 4.8% (one of 21) of healthy participants in a control group showed one or more persistent symptoms.

Hypertension was the most common (13%) comorbidity in patients. The most common persistent symptoms were fatigue (13.6%) and loss of smell or taste (13.6%), which is consistent with previous findings.

The researchers noted several limitations, including the small sample size, a single study site, possible biases due to self-reporting, and loss of follow-up care in 57 participants.

“To the best of our knowledge, this study provides the longest symptom follow-up after COVID-19 infection,” the authors wrote.

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