Chunlan Zhang, 1 Xi Chen, 1 Jingping Li, 2 Zhenqi Liu, 3 Wei Liu, 2 Jingjing Zhang, 1 Zhiguang Zhou
1National Metabolic Diseases Clinical Research Center, Metabolic Syndrome Research Center, Key Diabetes Immunology Laboratory, Ministry of Education, Metabolism and Endocrinology Department, Central South University Second Xiangya Hospital, Changsha, Hunan, 410011, People’s Republic of China; 2 Department of Metabolic Surgery, Biliopancreatic Surgery Department, Xiangya Second Hospital, Central South University, Changsha, Hunan, 410011, People’s Republic of China; 3 Division of Endocrinology and Metabolism, Department of Medicine, University of Virginia Health System, Charlottesville, VA, USA
Correspondence: Jingjing Zhang
National Metabolic Disease Clinical Research Center, Metabolic Syndrome Research Center, Key Diabetes Immunology Laboratory, Ministry of Education, Metabolism and Endocrinology Department, Central South University Second Xiangya Hospital, 139 Renmin Middle Road, Changsha, Hunan, People’s Republic of China
Tel +86 731-85292154
E-mail [email protected]
Wei Liu
Metabolic Surgery Department, Biliopancreatic Surgery Department, Xiangya Second Hospital, Central South University, 139 Renmin Middle Road, Changsha, Hunan, People’s Republic of China
Tel +86 731-85292154
E-mail [email protected]
Background: Laparoscopic sleeve gastrectomy (LSG) is currently a predominant bariatric procedure. However, there is little data on the dietary effects of this procedure on Chinese patients. The aim of this study was to assess the prevalence of nutrient deficiency after LSG in Chinese patients.
Methods: Eighty-two obese patients were recruited from Central South University’s Second Xiangya Hospital, and all patients underwent LSG and ended the visit.
Results: Compared to baseline, serum albumin levels increased significantly 1–12 months (P <0.001) after surgery, and the rate of hypoalbuminemia decreased from 8.5% to 0% (P = 0.063) throughout the study. Anemia was present in 7.3% of all patients before surgery and its prevalence increased to 11.0% (P = 0.109) 12 months after surgery. The rate of anemia in fertile women was higher than that of men (21.4% versus 2.3%, P = 0.036). No significant changes in vitamin B12 deficiency were noted throughout the study (0% versus 3.8%, P = 1.0). The increase in folate deficiency was only observed in the female group (3.7% versus 20%, P = 0.031) and the group without obesity without type 2 diabetes (T2D) according to LSG (27.3% versus 47.1%, P = 0.031). A decrease in ferritin levels and an increase in iron deficiency were noted in all patients 12 months after surgery.
Conclusion: Based on a 12 month follow-up period, LSG is effective in controlling metabolic syndrome and has little impact on nutritional deficiencies, suggesting that LSG is an effective and comparatively safe procedure for Chinese patients that addresses nutritional deficits 12 months after surgery.
Keywords: Anemia, laparoscopic sleeve gastrectomy, diet, obesity
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