Infectious Disease

COVID-19 mortality price for intubated adults decrease than beforehand reported

HealthDay News – Most patients with COVID-19 in the intensive care unit (ICU) recover with a 35.7 percent death rate for those on mechanical ventilation. This is according to a study published online May 26 in Critical Care Medicine.

Sara C. Auld, MD, of the Emory Critical Care Center in Atlanta, and colleagues conducted an observational study of patients admitted to six COVID-19-named intensive care units within an Atlanta academic health center from March 6 to April 17, 2020. Data were included for 217 critically ill patients.

The researchers found that 35.7 percent of the 165 patients who required mechanical ventilation died, with 4.8 percent of the patients still on the ventilator at the time of writing. The overall mortality within the cohort was 30.9 percent; 60.4 percent of the patients survived discharge from the hospital. Significant associations were found for mortality with increasing age, a lower body mass index, chronic kidney disease, a higher score for the assessment of sequential organ failure, a lower ratio of arterial oxygen partial pressure to fractionated inspired oxygen, a higher D-dimer, a higher C-reactive protein and receiving ventilation, vasopressors, renal replacement therapy, or vasodilator therapy.

“These results suggest that most patients with acute respiratory failure can recover from COVID-19, even with severe medical conditions that require intubation and mechanical ventilation,” the authors write.

Abstract / full text



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